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Research papers on Neuroplasticity and learning

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  2. Neuroplasticity and brain repair after stroke

    Steven C. Cramer, Jeffrey D. Riley · 2008 · Current Opinion in Neurology · 182 citations

    PURPOSE OF REVIEW: This review considers recent insights into the neurobiology of repair after stroke in animals and humans, the range of emerging therapies to promote repair and recovery after the acute phase of stroke, and issues related to optimizing trials of such therapies. RECENT FINDINGS: Animal studies continue to shed light on the molecular, vascular, glial, neuronal, behavioral, and environmental events that are important to the spontaneous behavioral recovery that is observed during the weeks after a stroke. Animal and human studies are examining a wide range of potential interventions that may favorably modify outcome, including small molecules, growth factors, cell-based approac

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  3. How Musical Training Shapes the Adult Brain: Predispositions and Neuroplasticity

    Alicja Małgorzata Olszewska, Maciej Gaca, Aleksandra Maria Herman, et al. · 2021 · Frontiers in Neuroscience · 133 citations

    Learning to play a musical instrument is a complex task that integrates multiple sensory modalities and higher-order cognitive functions. Therefore, musical training is considered a useful framework for the research on training-induced neuroplasticity. However, the classical nature-or-nurture question remains, whether the differences observed between musicians and non-musicians are due to predispositions or result from the training itself. Here we present a review of recent publications with strong focus on experimental designs to better understand both brain reorganization and the neuronal markers of predispositions when learning to play a musical instrument. Cross-sectional studies identif

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  4. Brain Neuroplasticity Leveraging Virtual Reality and Brain–Computer Interface Technologies

    Athanasios S. Drigas, Angeliki Sideraki · 2024 · Sensors · 128 citations

    This study explores neuroplasticity through the use of virtual reality (VR) and brain-computer interfaces (BCIs). Neuroplasticity is the brain's ability to reorganize itself by forming new neural connections in response to learning, experience, and injury. VR offers a controlled environment to manipulate sensory inputs, while BCIs facilitate real-time monitoring and modulation of neural activity. By combining VR and BCI, researchers can stimulate specific brain regions, trigger neurochemical changes, and influence cognitive functions such as memory, perception, and motor skills. Key findings indicate that VR and BCI interventions are promising for rehabilitation therapies, treatment of phobi

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  6. Endocrine regulation of cognition and neuroplasticity: Our pursuit to unveil the complex interaction between hormones, the brain, and behaviour.

    Liisa A.M. Galea, Kristina A. Uban, Jonathan R. Epp, et al. · 2008 · Canadian Journal of Experimental Psychology/Revue canadienne de psychologie expérimentale · 122 citations

    Gonadal and stress hormones modulate neuroplasticity and behaviour. This review focuses on our findings over the past decade on the effects of estrogens and androgens on hippocampal neurogenesis, hippocampus-dependent learning and memory and the effects of reproductive experience in the rodent. Evidence suggests that acute estradiol initially enhances and subsequently suppresses cell proliferation in the dentate gyrus of adult female rodents. Repeated exposure to estradiol modulates hippocampal neurogenesis and cell death in adult female, but not male, rodents while, testosterone and dihydrotestosterone upregulate hippocampal neurogenesis in adult male rodents. Estradiol dose-dependently aff

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  7. Neuroplasticity

    Moheb Costandi · 2016 · The MIT Press eBooks · 113 citations

    The real story of how our brains and nervous systems change throughout our lifetimes—with or without “brain training.” Fifty years ago, neuroscientists thought that a mature brain was fixed like a fly in amber, unable to change. Today, we know that our brains and nervous systems change throughout our lifetimes. This concept of neuroplasticity has captured the imagination of a public eager for self-improvement—and has inspired countless Internet entrepreneurs who peddle dubious “brain training” games and apps. In this book, Moheb Costandi offers a concise and engaging overview of neuroplasticity for the general reader, describing how our brains change continuously in response to our actions a

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  8. Augmenting NMDA receptor signaling boosts experience-dependent neuroplasticity in the adult human brain

    Jennifer K. Forsyth, Peter Bachman, Daniel H. Mathalon, et al. · 2015 · Proceedings of the National Academy of Sciences · 78 citations

    Experience-dependent plasticity is a fundamental property of the brain. It is critical for everyday function, is impaired in a range of neurological and psychiatric disorders, and frequently depends on long-term potentiation (LTP). Preclinical studies suggest that augmenting N-methyl-d-aspartate receptor (NMDAR) signaling may promote experience-dependent plasticity; however, a lack of noninvasive methods has limited our ability to test this idea in humans until recently. We examined the effects of enhancing NMDAR signaling using d-cycloserine (DCS) on a recently developed LTP EEG paradigm that uses high-frequency visual stimulation (HFvS) to induce neural potentiation in visual cortex neuron

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  9. Functional and Dysfunctional Neuroplasticity in Learning to Cope with Stress

    Simona Cabib, Paolo Campus, David Conversi, et al. · 2020 · Brain Sciences · 33 citations

    In this brief review, we present evidence of the primary role of learning-associated plasticity in the development of either adaptive or maladaptive coping strategies. Successful interactions with novel stressors foster plasticity within the neural circuits supporting acquisition, consolidation, retrieval, and extinction of instrumental learning leading to development of a rich repertoire of flexible and context-specific adaptive coping responses, whereas prolonged or repeated exposure to inescapable/uncontrollable stressors fosters dysfunctional plasticity within the learning circuits leading to perseverant and inflexible maladaptive coping strategies. Finally, the results collected using a

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  10. Brain-Inspired Multisensory Learning: A Systematic Review of Neuroplasticity and Cognitive Outcomes in Adult Multicultural and Second Language Acquisition

    Evgenia Gkintoni, Stephanos P. Vassilopoulos, Georgios Nikolaou · 2025 · Biomimetics · 32 citations

    Background: Multicultural education and second-language acquisition engaged neural networks, supporting executive function, memory, and social cognition in adulthood, represent powerful forms of brain-inspired multisensory learning. The neuroeducational framework integrates neuroscience with pedagogical practice to understand how linguistically and culturally rich environments drive neuroplasticity and cognitive adaptation in adult learners. Objective: This systematic review synthesizes findings from 80 studies examining neuroplasticity and cognitive outcomes in adults undergoing multicultural and second-language acquisition, focusing on underlying neural mechanisms and educational effective

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  13. Experience-Dependent Neuroplasticity in the Hippocampus of Bilingual Young Adults

    Federico Gallo, Toms Voits, Jason Rothman, et al. · 2025 · eNeuro · 6 citations

    Models of experience-dependent neuroplasticity predict that the acquisition and extensive use of a new skill trigger a nonlinear trajectory of neurostructural modifications, where initial expansion of relevant brain areas subsequently (once the skill is acquired) gives way to volumetric renormalization. Such predictions also apply in the domain of language during learning and/or simultaneous management of two (or more) linguistic systems. In a sample of 69 young adult Russian-English bilinguals, we tested the hypothesis that individual differences in bilingual engagement nonlinearly correlate with normalized volume of the hippocampus-a key learning-related brain region particularly amenable

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  15. Neuroplasticity And Adult Learning: Can An Old Dog Learn New Tricks?

    Andriana Eliadis · 2024 · Educational Administration: Theory and Practice

    Adult learning has always remained a topic of discussion among researchers. Thus, this study aimed to extend this debate in the context of literature. This is a qualitative literature-based review that has focused on prior studies. Following the comprehensive inclusion and exclusion criteria, the data was gathered from academic journals and books. The results reported a strong connection between neuroplasticity and adult learning. They negated the old dogma that the brain's cells never regenerate, and adults cannot learn as effectively as when they were young. The findings highlighted that adults taking a healthy and nutritional diet and exercising regularly can learn as effectively as the y

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  16. The Impact of Digital Technologies and AI on Adult Learning: From Digital Literacy to Neuroplasticity

    Yana Topolnyk, Roman Gurevych, Ihor Debenko, et al. · 2025 · BRAIN. Broad Research in Artificial Intelligence and Neuroscience

    This article explores the urgent issue of developing digital skills and stimulating neuroplasticity in adults during rapid digital transformation. It examines how information and communication technologies (ICT) and artificial intelligence (AI) contribute to effective adult education. The article analyses the theoretical foundations of digital literacy and neuroplasticity. It also discusses practical strategies for enhancing these areas through ICT and AI. To support this analysis, the study applies several research methods. These include a theoretical review of scientific literature, comparative analysis, and case study approaches. The methods are used to investigate real-life examples of a

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  18. Neuroplasticity in Adult Learning: Underlying Mechanisms and Therapeutic Applications

    Shyma Kareem, Anand Bhuyar · 2026 · Journal of Artificial Intelligence and Information

    This review examines the current understanding of neuroplasticity in adult learning, focusing on cellular mechanisms, therapeutic applications, and implications for rehabilitation and education. Recent advances in neuroscience have revolutionized our understanding of the brain's capacity for change throughout adulthood, challenging traditional notions of fixed neural architecture. This paper synthesizes findings from molecular studies, clinical trials, and cognitive research to present a comprehensive overview of adult neuroplasticity and its practical applications in therapeutic contexts. The scope of this review encompasses research conducted between 2015 and 2024, highlighting significant

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