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Research papers on Exercise and depression

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  2. Exercise for the Treatment of Depression

    Jan Knapen, Davy Vancampfort, Bea Schoubs, et al. · 2009 · The Open Complementary Medicine Journal · 911 citations

    Depression is a common mental disorder that presents with depressed mood, loss of interest or pleasure, feelings of guilt or low self-worth, disturbed sleep and/or appetite, low energy, and poor concentration.Depression is a widespread and often chronic condition.Lifetime prevalence estimates for major depressive disorder are approximately 15% to 20%; 1-year prevalence estimates are 5% to 10%.Moreover, depression is characterized by high rates of relapse: 22% to 50% of patients suffer recurrent episodes within 6 months after recovery.Depression is associated with a high incidence of co-morbid somatic illness.Individuals suffering from major depression run a higher relative risk of coronary h

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  4. Exercise in prevention and treatment of anxiety and depression among children and young people

    Lillebeth Larun, Lena Victoria Nordheim, Eilin Ekeland, et al. · 2006 · Cochrane Database of Systematic Reviews · 492 citations

    BACKGROUND: Depression and anxiety are common psychological disorders for children and adolescents. Psychological (e.g. psychotherapy), psychosocial (e.g. cognitive behavioral therapy) and biological (e.g. SSRIs or tricyclic drugs) treatments are the most common treatments being offered. The large variety of therapeutic interventions give rise to questions of clinical effectiveness and side effects. Physical exercise is inexpensive with few, if any, side effects. OBJECTIVES: To assess the effects of exercise interventions in reducing or preventing anxiety or depression in children and young people up to 20 years of age. SEARCH STRATEGY: We searched the Cochrane Controlled Trials Register (la

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  5. Exercise therapy improves both mental and physical health in patients with major depression

    Jan Knapen, Davy Vancampfort, Yves Moriën, et al. · 2014 · Disability and Rehabilitation · 394 citations

    PURPOSE: to present clinical guidelines for exercise therapy in depressed patients derived from recent meta-analyses. METHOD: four meta-analyses on effects of physical exercise on mental and physical in depression were analysed. RESULTS: For mild to moderate depression the effect of exercise may be comparable to antidepressant medication and psychotherapy; for severe depression exercise seems to be a valuable complementary therapy to the traditional treatments. Depression is associated with a high incidence of co-morbid somatic illnesses, especially cardiovascular diseases, type 2 diabetes and metabolic syndrome. Exercise is extremely powerful in preventing and treating these diseases. Physi

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  6. Impact of physical exercise on depression and anxiety in adolescent inpatients: A randomized controlled trial

    Arnaud Philippot, Vincent Dubois, Kate Lambrechts, et al. · 2022 · Journal of Affective Disorders · 214 citations

    BACKGROUND: Physical exercise therapy is of proven efficacy in the treatment of adults with depression, but corresponding evidence is lacking in depressed adolescent inpatients. The aim of this study was to document the effect of add-on treatment with structured physical exercise in a clinical population of adolescents hospitalized for depression and anxiety in a psychiatric hospital. METHODS: A group of 52 adolescent inpatients was randomly assigned to a physical exercise or control program three to four times per week over a six-week period (20 hours in total). The primary outcome was the Hospital Anxiety Depression Scale (HADS) for evaluation of depression and anxiety symptoms. Secondary

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  8. Placebo Effect in the Treatment of Depression and Anxiety

    Irving Kirsch · 2019 · Frontiers in Psychiatry · 205 citations

    The aim of this review is to evaluate the placebo effect in the treatment of anxiety and depression. Antidepressants are supposed to work by fixing a chemical imbalance, specifically, a lack of serotonin or norepinephrine in the brain. However, analyses of the published and the unpublished clinical trial data are consistent in showing that most (if not all) of the benefits of antidepressants in the treatment of depression and anxiety are due to the placebo response, and the difference in improvement between drug and placebo is not clinically meaningful and may be due to breaking blind by both patients and clinicians. Although this conclusion has been the subject of intense controversy, the c

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  10. Exercise in the treatment of major depression: A systematic review grading the quality of evidence

    Louise Danielsson, A Noras, Margda Wærn, et al. · 2013 · Physiotherapy Theory and Practice · 84 citations

    OBJECTIVE: To examine the quality of evidence for exercise in the treatment of major depression, comparing specific study types; aerobic exercise vs. antidepressants, aerobic exercise vs. any physical activity, and aerobic exercise as augmentation therapy to treatment as usual vs. treatment as usual. METHODS: Electronic searches for randomized controlled studies, reporting on treatment outcome in adults with major depression confirmed by a clinical interview. Quality of evidence was assessed using the Grading and Recommendations Assessment, Development and Evaluation and an additional risk of bias-protocol. RESULTS: Fourteen eligible studies were retrieved, of which nine had low risk of bias

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  11. Effect of physical exercise intervention on mood and frontal alpha asymmetry in internet gaming disorder

    Ji-Sun Hong, S. Kim, K. Kang, et al. · 2020 · Mental Health and Physical Activity · 47 citations

    Abstract Purpose We aimed to evaluate the effect and neurophysiological mechanism of physical exercise intervention combined with cognitive behavioral therapy on mood and frontal alpha asymmetry in the treatment of Internet gaming disorder. Methods Fifty male adolescents with Internet gaming disorder were randomly assigned to one of two groups. In the cognitive behavioral therapy + physical exercise group (CBT + PE group, n = 25), participants underwent eight sessions of cognitive behavioral therapy and six sessions of exercise intervention; in the cognitive behavioral therapy-only group (CBT-only group, n = 25), participants underwent eight sessions of cognitive behavioral therapy and six s

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  12. Is physical exercise and dietary therapy a feasible alternative to cognitive behavior therapy in treatment of eating disorders? A randomized controlled trial of two group therapies

    T. F. Mathisen, J. Rosenvinge, Oddgeir Friborg, et al. · 2020 · The International Journal of Eating Disorders · 43 citations

    Abstract Objective To compare effects of physical exercise and dietary therapy (PED‐t) to cognitive behavioral therapy (CBT) in treatment of bulimia nervosa (BN) and binge‐eating disorder (BED). Method The active sample (18–40 years of age) consisted of 76 women in the PED‐t condition and 73 in the CBT condition. Participants who chose not to initiate treatment immediately (n = 23) were put on a waiting list. Outcome measures were the eating disorder examination questionnaire (EDE‐Q), Clinical Impairment Assessment (CIA), Satisfaction with Life Scale (SWLS), Beck Depression Inventory (BDI), and numbers in remission at posttreatment, and at 6‐, 12‐, and 24‐months follow‐up. Results Both treat

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  13. Effects of physical exercise intervention on depressive and anxious moods of college students: A meta-analysis of randomized controlled trials

    Xiang Huang, Yin-Jia Wang, Hui-Hong Zhang · 2023 · Asian Journal of Sport and Exercise Psychology · 43 citations

    Background Due to the limitation of drug treatment and other adverse reactions, many psychological treatments always adopt rehabilitation training or non-drug intervention methods, while physical exercise is considered as an auxiliary way. A mass of literature has verified the therapeutic benefits of physical exercise to reduce depression and anxiety in clinical populations. However, little attention is paid to the mental health benefits of exercise for non-clinical populations. The purpose of this meta-analysis is to systematically aggregate and quantify findings of the effect of physical exercise on depression and anxiety in non-clinical populations, through which to evaluate whether physi

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  14. Physical exercise and depression

    Sebastian Eriksson, Gunvor E. Gard · 2011 · Physical Therapy Reviews · 40 citations

    Objectives: The objective was to review studies which used physical exercise as an intervention to treat major depression, focusing on methodology, mechanisms of action, types of physical exercise and treatment outcomes.Methods: Perform a search of the literature in the databases PsycINFO and PubMed 2000–2010 with ‘major depression’, ‘exercise’, ‘outcome’, ‘physical activity’ and ‘aerobic training’ as search terms. The inclusion criteria were: RCT treating depression with physical exercise with no limitations concerning age, gender or medication status.Results: Eight studies fulfilled the inclusion criteria and were included. Seven of the eight studies showed significantly improved mood and

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  15. “Crawling Out of the Cocoon”: Patients' Experiences of a Physical Therapy Exercise Intervention in the Treatment of Major Depression

    Louise Danielsson, Birgitta Kihlbom, Susanne Rosberg · 2016 · Physical Therapy · 22 citations

    Background: Although the effectiveness of physical exercise for depression has been studied for many years, few studies have described patients' experiences of what exercise means to them, beyond the biological focus. Moreover, exercise as a treatment for depression is rarely explored in a physical therapy context. Objectives: The purpose of this study was to explore a physical therapy exercise intervention, as experienced by people with major depression. Design: This study had an inductive approach and used qualitative content analysis. Methods: Semistructured interviews were conducted with 13 people who participated in physical therapist–guided aerobic exercise in a randomized controlled t

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  16. Effect of different physical activity interventions on perinatal depression: a systematic review and network meta-analysis

    Yu Shuai, Jinlong Wu, Chen-Mu Li, et al. · 2024 · BMC Public Health · 20 citations

    Perinatal depression can have profound impacts on both families and society. Exercise therapy is gradually becoming a widely used adjunct treatment for perinatal depression. Some studies have already focused on the relationship between physical activity and perinatal depression (PND). However, there is currently a lack of systematic and comprehensive evidence to address the crucial question of making optimal choices among different forms of physical activity. This study aims to compare and rank different physical activity intervention strategies and identify the most effective one for perinatal depression. Four databases, namely PubMed, Cochrane Library, Embase, and Web of Science, were sear

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  17. Analysis of the Effect of Different Physical Exercise Protocols on Depression in Adults: Systematic Review and Meta-analysis of Randomized Controlled Trials

    Érica M. Correia, D. Monteiro, T. Bento, et al. · 2023 · Sports Health · 17 citations

    Context: Physical exercise (PE) is an effective treatment for depression, alone or as an adjunct. Objective: There is a lack of indicators regarding the frequency, intensity, duration, and type of physical exercise (PE). This study aims to synthesize and analyze the dose-effect of different PE protocols in adult subjects in the treatment of depression, based on the analysis of randomized controlled trials (RCTs). Data Sources: The search was conducted using Web of Science, PubMed, and Cochrane Library electronic databases. Study Selection: Studies with an exercise-based intervention published by December 31, 2021 were identified. RCTs and meta-analyses involving adults with depression were a

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  20. Effect of Regular Physical Exercise on Gut Microbiota and Depressive Behaviors in Rats

    Liang-ju Sheng, Yuxuan Wang, Anqi Jiang, et al. · 2021 · Journal of Food Quality · 10 citations

    Objective. The gut microbiota, as the critical mediator of the gut-brain axis, can produce and transport neuroactive substances, thus playing a significant role in the pathogenesis of depression. Although regular physical exercise is an important nondrug antidepressant, its specific effector mechanism is still unclear. Methods. Rats were randomly divided into four different groups (n = 10 for each group) as follows: normal group (G1), depression group (G2), fluoxetine treatment group (G3), and regular exercise treatment group (G4). All rats underwent forced swimming tests, tail suspension tests, open field tests, and elevated plus-maze tests to detect behavioristics. Then, corticosterone lev

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  21. Immunological Effects of an Add-On Physical Exercise Therapy in Depressed Adolescents and Its Interplay with Depression Severity

    H. Wunram, M. Oberste, S. Hamacher, et al. · 2021 · International Journal of Environmental Research and Public Health · 10 citations

    Background: Pro-inflammatory cytokines (PICs) have gained attention in the pathophysiology and treatment of depressive disorders. At the same time, the therapeutic effect of physical activity seems to work via immunomodulatory pathways. The interventional study “Mood Vibes” analyzed the influence of exercise on depression severity (primary endpoint) in depressive adolescents; the influence of PICs on the clinical outcome was analyzed as a secondary endpoint. Methods: Clinically diagnosed depressed adolescents (N = 64; 28.1% male; mean age = 15.9; mean BMI = 24.6) were included and participated either in Whole Body Vibration (WBV) (n = 21) or bicycle ergometer training (n = 20) in addition to

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  22. Effect of physical activity on depression, anxiety, and stress in women surviving breast cancer: A systematic review and meta-analysis of randomized clinical trials

    Monte Nero Dario da Silva, Carlos Rodrigo Nascimento de Lira, Cláudio Luiz da Silva Lima Paz, et al. · 2024 · Journal of Health Psychology · 9 citations

    Breast cancer treatment can lead to psychological distress, including depression, anxiety, and stress. We systematically investigated the effect of physical exercise on these factors in women surviving breast cancer (WSBC). Eight databases were searched to identify eligible randomized controlled trials (RCTs). Data extraction and bias risk analysis were conducted using standardized tools, with meta-analysis performed using Review Manager software. Out of 3529 documents initially identified, 15 RCTs were included, comprising 2756 WSBC (1284 in intervention groups and 1472 in control groups), with 2082 participants in depression analyses, 513 in anxiety analyses, and 161 in stress analyses. Me

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