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Papers on “long covid post-acute sequelae symptoms”

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  3. Characterizing long COVID in an international cohort: 7 months of symptoms and their impact

    Hannah Davis, Gina Assaf, Lisa McCorkell, et al. · 2021 · EClinicalMedicine · 3,045 cites

    BACKGROUND: A significant number of patients with COVID-19 experience prolonged symptoms, known as Long COVID. Few systematic studies have investigated this population, particularly in outpatient settings. Hence, relatively little is known about symptom makeup and severity, expected clinical course, impact on daily functioning, and return to baseline health. METHODS: We conducted an online survey of people with suspected and confirmed COVID-19, distributed via COVID-19 support groups (e.g. Body Politic, Long COVID Support Group, Long Haul COVID Fighters) and social media (e.g. Twitter, Facebook). Data were collected from September 6, 2020 to November 25, 2020. We analyzed responses from 3762

  5. Management of post-acute covid-19 in primary care

    Trisha Greenhalgh, Matthew Knight, Christine A’Court, et al. · 2020 · BMJ · 1,797 cites

    What you need to know• Management of covid-19 after the first three weeks is currently based on limited evidence • Approximately 10% of people experience prolonged illness after covid-19 • Many such patients recover spontaneously (if slowly) with holistic support, rest, symptomatic treatment, and gradual increase in activity • Home pulse oximetry can be helpful in monitoring breathlessness • Indications for specialist assessment include clinical concern along with respiratory, cardiac, or neurological symptoms that are new, persistent, or progressive

  7. Characterising long COVID: a living systematic review

    Melina Michelen, Lakshmi Manoharan, Natalie Elkheir, et al. · 2021 · BMJ Global Health · 989 cites

    Background While it is now apparent clinical sequelae (long COVID) may persist after acute COVID-19, their nature, frequency and aetiology are poorly characterised. This study aims to regularly synthesise evidence on long COVID characteristics, to help inform clinical management, rehabilitation strategies and interventional studies to improve long-term outcomes. Methods A living systematic review. Medline, CINAHL (EBSCO), Global Health (Ovid), WHO Global Research on COVID-19 database, LitCovid and Google Scholar were searched till 17 March 2021. Studies including at least 100 people with confirmed or clinically suspected COVID-19 at 12 weeks or more post onset were included. Risk of bias was

  8. Long COVID or Post-acute Sequelae of COVID-19 (PASC): An Overview of Biological Factors That May Contribute to Persistent Symptoms

    Amy D. Proal, Michael B. VanElzakker · 2021 · Frontiers in Microbiology · 936 cites

    The novel virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a pandemic of coronavirus disease 2019 (COVID-19). Across the globe, a subset of patients who sustain an acute SARS-CoV-2 infection are developing a wide range of persistent symptoms that do not resolve over the course of many months. These patients are being given the diagnosis Long COVID or Post-acute sequelae of COVID-19 (PASC). It is likely that individual patients with a PASC diagnosis have different underlying biological factors driving their symptoms, none of which are mutually exclusive. This paper details mechanisms by which RNA viruses beyond just SARS-CoV-2 have be connected to long-term health

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