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Papers on “personalized precision medicine genomics”

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1. Engineering precision nanoparticles for drug delivery

   Michael J. Mitchell, Margaret M. Billingsley, Rebecca M. Haley, et al. · 2020 · Nature Reviews Drug Discovery · 7,751 cites

2. Radiomics: the bridge between medical imaging and personalized medicine

   Philippe Lambin, Ralph T. H. Leijenaar, Timo M. Deist, et al. · 2017 · Nature Reviews Clinical Oncology · 5,773 cites

3. Precision Medicine, AI, and the Future of Personalized Health Care

   Kevin B. Johnson, Wei‐Qi Wei, Dilhan Weeraratne, et al. · 2020 · Clinical and Translational Science · 1,828 cites

   The convergence of artificial intelligence (AI) and precision medicine promises to revolutionize health care. Precision medicine methods identify phenotypes of patients with less-common responses to treatment or unique healthcare needs. AI leverages sophisticated computation and inference to generate insights, enables the system to reason and learn, and empowers clinician decision making through augmented intelligence. Recent literature suggests that translational research exploring this convergence will help solve the most difficult challenges facing precision medicine, especially those in which nongenomic and genomic determinants, combined with information from patient symptoms, clinical h

4. Personalized medicine: Time for one-person trials

   Nicholas J. Schork · 2015 · Nature · 1,242 cites

5. Targeted drug delivery strategies for precision medicines

   Mandana T. Manzari, Yosi Shamay, Hiroto Kiguchi, et al. · 2021 · Nature Reviews Materials · 1,163 cites

6. Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine

   Chantal Pauli, Benjamin D. Hopkins, Davide Prandi, et al. · 2017 · Cancer Discovery · 966 cites

   Abstract Precision medicine is an approach that takes into account the influence of individuals' genes, environment, and lifestyle exposures to tailor interventions. Here, we describe the development of a robust precision cancer care platform that integrates whole-exome sequencing with a living biobank that enables high-throughput drug screens on patient-derived tumor organoids. To date, 56 tumor-derived organoid cultures and 19 patient-derived xenograft (PDX) models have been established from the 769 patients enrolled in an Institutional Review Board–approved clinical trial. Because genomics alone was insufficient to identify therapeutic options for the majority of patients with advanced di

7. Genomic and transcriptomic profiling expands precision cancer medicine: the WINTHER trial

   Jordi Rodón, Jean‐Charles Soria, Raanan Berger, et al. · 2019 · Nature Medicine · 608 cites

8. Precision Public Health for the Era of Precision Medicine

   Muin J. Khoury, Michael F. Iademarco, William T. Riley · 2015 · American Journal of Preventive Medicine · 583 cites