FolioStart free

Biology · Literature

Research papers on Synthetic biology

Recent and highly-cited academic work on synthetic biology, gathered from Semantic Scholar, CrossRef and OpenAlex.

Search all 200M+ papers on this topic, free →Or track new synthetic biology papers automatically as they publish

  2. Effects of textile dyes on health and the environment and bioremediation potential of living organisms

    Bruno Lellis, Cíntia Zani Fávaro-Polonio, João Alencar Pamphile, et al. · 2019 · Biotechnology Research and Innovation · 2,761 citations

    The water is an essential resource for life on the planet and for human development. The textile industry is one of the anthropogenic activities that most consume water and pollute water bodies. Therefore, the present work aims to undertake a review on the main effects of the release of industrial dyes and the essential bioremediation mechanisms. The textile dyes significantly compromise the aesthetic quality of water bodies, increase biochemical and chemical oxygen demand (BOD and COD), impair photosynthesis, inhibit plant growth, enter the food chain, provide recalcitrance and bioaccumulation, and may promote toxicity, mutagenicity and carcinogenicity. In spite of this, the bioremediation

    Save this paper

  4. Dispersing biofilms with engineered enzymatic bacteriophage

    Timothy K. Lu, James J. Collins · 2007 · Proceedings of the National Academy of Sciences · 892 citations

    Synthetic biology involves the engineering of biological organisms by using modular and generalizable designs with the ultimate goal of developing useful solutions to real-world problems. One such problem involves bacterial biofilms, which are crucial in the pathogenesis of many clinically important infections and are difficult to eradicate because they exhibit resistance to antimicrobial treatments and removal by host immune systems. To address this issue, we engineered bacteriophage to express a biofilm-degrading enzyme during infection to simultaneously attack the bacterial cells in the biofilm and the biofilm matrix, which is composed of extracellular polymeric substances. We show that t

    Save this paper

  6. Engineered Living Materials: Prospects and Challenges for Using Biological Systems to Direct the Assembly of Smart Materials

    Peter Q. Nguyen, Noémie‐Manuelle Dorval Courchesne, Anna Duraj‐Thatte, et al. · 2018 · Advanced Materials · 591 citations

    Vast potential exists for the development of novel, engineered platforms that manipulate biology for the production of programmed advanced materials. Such systems would possess the autonomous, adaptive, and self-healing characteristics of living organisms, but would be engineered with the goal of assembling bulk materials with designer physicochemical or mechanical properties, across multiple length scales. Early efforts toward such engineered living materials (ELMs) are reviewed here, with an emphasis on engineered bacterial systems, living composite materials which integrate inorganic components, successful examples of large-scale implementation, and production methods. In addition, a conc

    Save this paper

  10. Synthetic biology of cyanobacteria: unique challenges and opportunities

    Bertram M. Berla, Rajib Saha, Cheryl M. Immethun, et al. · 2013 · Frontiers in Microbiology · 308 citations

    Photosynthetic organisms, and especially cyanobacteria, hold great promise as sources of renewably-produced fuels, bulk and specialty chemicals, and nutritional products. Synthetic biology tools can help unlock cyanobacteria's potential for these functions, but unfortunately tool development for these organisms has lagged behind that for S. cerevisiae and E. coli. While these organisms may in many cases be more difficult to work with as "chassis" strains for synthetic biology than certain heterotrophs, the unique advantages of autotrophs in biotechnology applications as well as the scientific importance of improved understanding of photosynthesis warrant the development of these systems into

    Save this paper

  23. Growing Long-chain Polymers in vitro Using Engineered Bacteria in Synthetic Biology and Precision Fermentation Space

    Pranav Bhaskar · 2024 · The Applied Biology & Chemistry Journal

    The synthesis of long-chain polymers has a conventional method of utilizing energy-intensive chemical procedures, which are normally not eco-friendly. Though synthesizing polymers using synthetic biology and precision fermentation is not possible in vitro, both methods, when integrated, provide a biological solution to synthesize polymers in vitro. In light of this, this article examines the means of engineering bacteria, including Escherichia coli and Pseudomonas, that are used to produce controlled synthesis of high-value polymers like PHAs and PLA. New technologies and methodologies of synthetic biology, including the CRISPR-Cas9 system, have brought bacterial metabolic engineering to new

    Save this paper

Write your paper with these sources

Folio is the integrity-first research workspace: search 200M+ papers, save sources, and write with citations that format themselves. Free for students and researchers.

Start writing free →