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Research papers on Maternal mortality

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  1. Correspondence - Tranexamic acid for traumatic brain injury

    Marina Romanello, Claudia Di Napoli, Paul Drummond, et al. · 2005 · London School of Economics and Political Science Research Online (London School of Economics and Political Science) · 11,873 citations

    BACKGROUND: In early breast cancer, variations in local treatment that substantially affect the risk of locoregional recurrence could also affect long-term breast cancer mortality. To examine this relationship, collaborative meta-analyses were undertaken, based on individual patient data, of the relevant randomised trials that began by 1995. METHODS: Information was available on 42,000 women in 78 randomised treatment comparisons (radiotherapy vs no radiotherapy, 23,500; more vs less surgery, 9300; more surgery vs radiotherapy, 9300). 24 types of local treatment comparison were identified. To help relate the effect on local (ie, locoregional) recurrence to that on breast cancer mortality, th

  2. Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the Global Burden of Disease Study 2017

    Gregory A. Roth, Degu Abate, Kalkidan Hassen Abate, et al. · 2018 · The Lancet · 8,741 citations

    BACKGROUND: Global development goals increasingly rely on country-specific estimates for benchmarking a nation's progress. To meet this need, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 estimated global, regional, national, and, for selected locations, subnational cause-specific mortality beginning in the year 1980. Here we report an update to that study, making use of newly available data and improved methods. GBD 2017 provides a comprehensive assessment of cause-specific mortality for 282 causes in 195 countries and territories from 1980 to 2017. METHODS: The causes of death database is composed of vital registration (VR), verbal autopsy (VA), registry, surve

  3. Racism as a Determinant of Health: A Systematic Review and Meta-Analysis

    Yin Paradies, Jehonathan Ben, Nida Denson, et al. · 2015 · PLoS ONE · 2,633 citations

    Despite a growing body of epidemiological evidence in recent years documenting the health impacts of racism, the cumulative evidence base has yet to be synthesized in a comprehensive meta-analysis focused specifically on racism as a determinant of health. This meta-analysis reviewed the literature focusing on the relationship between reported racism and mental and physical health outcomes. Data from 293 studies reported in 333 articles published between 1983 and 2013, and conducted predominately in the U.S., were analysed using random effects models and mean weighted effect sizes. Racism was associated with poorer mental health (negative mental health: r = -.23, 95% CI [-.24,-.21], k = 227;

  4. Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care

    MARC DE HERT, Christoph U. Correll, Julio Bobes, et al. · 2011 · World Psychiatry · 2,512 citations

    The lifespan of people with severe mental illness (SMI) is shorter compared to the general population. This excess mortality is mainly due to physical illness. We report prevalence rates of different physical illnesses as well as important individual lifestyle choices, side effects of psychotropic treatment and disparities in health care access, utilization and provision that contribute to these poor physical health outcomes. We searched MEDLINE (1966 - August 2010) combining the MeSH terms of schizophrenia, bipolar disorder and major depressive disorder with the different MeSH terms of general physical disease categories to select pertinent reviews and additional relevant studies through cr

  5. Global, regional, and national levels of maternal mortality, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

    Nicholas J Kassebaum, Ryan M Barber, Zulfiqar A Bhutta, et al. · 2016 · The Lancet · 1,212 citations

    BACKGROUND: In transitioning from the Millennium Development Goal to the Sustainable Development Goal era, it is imperative to comprehensively assess progress toward reducing maternal mortality to identify areas of success, remaining challenges, and frame policy discussions. We aimed to quantify maternal mortality throughout the world by underlying cause and age from 1990 to 2015. METHODS: We estimated maternal mortality at the global, regional, and national levels from 1990 to 2015 for ages 10-54 years by systematically compiling and processing all available data sources from 186 of 195 countries and territories, 11 of which were analysed at the subnational level. We quantified eight underl

  6. Determinants of use of maternal health services in Nigeria - looking beyond individual and household factors

    Stella Babalola, Adesegun Fatusi · 2009 · BMC Pregnancy and Childbirth · 858 citations

    BACKGROUND: Utilization of maternal health services is associated with improved maternal and neonatal health outcomes. Considering global and national interests in the Millennium Development Goal and Nigeria's high level of maternal mortality, understanding the factors affecting maternal health use is crucial. Studies on the use of maternal care services have largely overlooked community and other contextual factors. This study examined the determinants of maternal services utilization in Nigeria, with a focus on individual, household, community and state-level factors. METHODS: Data from the 2005 National HIV/AIDS and Reproductive Health Survey - an interviewer-administered nationally repre

  7. Reducing Disparities in Severe Maternal Morbidity and Mortality

    ELIZABETH A. HOWELL · 2018 · Clinical Obstetrics & Gynecology · 657 citations

    Significant racial and ethnic disparities in maternal morbidity and mortality exist in the United States. Black women are 3 to 4 times more likely to die a pregnancy-related death as compared with white women. Growing research indicates that quality of health care, from preconception through postpartum care, may be a critical lever for improving outcomes for racial and ethnic minority women. This article reviews racial and ethnic disparities in severe maternal morbidities and mortality, underlying drivers of these disparities, and potential levers to reduce their occurrence.

  8. A global analysis of the determinants of maternal health and transitions in maternal mortality

    João Paulo Souza, Louise T. Day, Ana Clara Rezende-Gomes, et al. · 2023 · The Lancet Global Health · 366 citations

    The reduction of maternal mortality and the promotion of maternal health and wellbeing are complex tasks. This Series paper analyses the distal and proximal determinants of maternal health, as well as the exposures, risk factors, and micro-correlates related to maternal mortality. This paper also examines the relationship between these determinants and the gradual shift over time from a pattern of high maternal mortality to a pattern of low maternal mortality (a phenomenon described as the maternal mortality transition). We conducted two systematic reviews of the literature and we analysed publicly available data on indicators related to the Sustainable Development Goals, specifically, estim

  9. How did Nepal Reduce the Maternal Mortality? A Result from Analysing the Determinants of Maternal Mortality

    R Karkee · 2012 · Journal of Nepal Medical Association · 10 citations

    Nepal reportedly reduced the maternal mortality ratio by 48% within one decade between 1996-2005 and received the Millennium development goal award for this. However, there is debate regarding the accuracy of this figure. On the basis of framework of determinants of maternal mortality proposed by McCarthy and Maine in 1992 and successive data from Nepal demographic health survey of 1996, 2001 and 2006, a literature analysis was done to identify the important factors behind this decline. Although facility delivery and skilled birth attendants are acclaimed as best strategy of reducing maternal mortality, a proportionate increase in these factors was not found to account the maternal mortality

  10. Conceptualizing Social Determinants of Maternal and Infant Health Disparities

    Susanne Klawetter · 2014 · Affilia · 8 citations

    Research demonstrates that women and children within marginalized ethnic and racial groups and those living in poverty experience disparate health outcomes. These disparities have immediate and long-term consequences. Exploring two theories used to examine social determinants of health—life course perspective and historical trauma response, this article will explain the major premises of each, provide application examples, compare and examine utility for practice, and highlight areas for future research. A theoretical critique will be included, as well as insight into how these theories together might address gaps as an approach to maternal and infant health research and practice.

  11. Determinants of Maternal Mortality in Nigeria

    Rabia Hashimu · 2025 · Zamfara International Journal Of Humanities

    Maternal mortality continues to pose a critical public health issue in Nigeria, which ranks among the countries with the highest maternal death rates worldwide. The leading causes of maternal mortality in Nigeria are a combination of medical conditions and socio-cultural factors, including obstetric hemorrhage, eclampsia, infections, and unsafe abortions. The general objective of this paper is to examine the social determinant of maternal mortality in Nigeria. These are preventable with timely and quality healthcare intervention. However, Nigeria's socio-economic and cultural context presents considerable challenges. High poverty levels, particularly in northern areas, limited healthcare fac

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